http://merkel-cell-carcinoma.com Just another WordPress weblog Wed, 28 May 2008 16:09:42 +0000 http://backend.userland.com/rss092 en Merkel cell carcinoma  , also called neuroendocrine  cancer  of the skin, is a rare type of disease in which malignant  (cancer) cells  are found on or just beneath the skin and in hair follicles  . Merkel cell carcinoma usually appears as firm, painless, shiny lumps of skin. These lumps or ... http://merkel-cell-carcinoma.com/2008/05/28/what-is-merkel-cell-carcinoma-2/ D. Pectasidesa, G. Papaxoinisa, E. Pectasidesa, H. Galanib, E. Razic, N. Katodrytise, G. Fountzilasd, T. Economopoulosa a2nd Department of Internal Medicine, Propaedeutic, Oncology Section, University of Athens, Attikon University Hospital, Haidari, b2nd Department of Medical Oncology, Henry Dunan Hospital,c2nd Department of Medical Oncology, Hygia Hospital, Athens, and dDepartment of Medical ... http://merkel-cell-carcinoma.com/2008/05/28/merkel-cell-carcinoma-of-the-skin-a-retrospective-study-of-24-cases-by-the-hellenic-cooperative-oncology-group/ Merkel cell carcinoma (MCC) is an aggressive tumor, the incidence of which is seemingly increased in immunocompromised patients. We report on a new case of MCC occurring in a 69-year-old male liver transplant recipient 6.5 years after transplantation. The outcome was marked by early skin and lymph node relapses treated ... http://merkel-cell-carcinoma.com/2008/05/28/merkel-cell-carcinoma-in-a-liver-transplant-patient/ Merkel cell carcinoma is an uncommon aggressive primary cutaneous neuroendocrine carcinoma. Histologically, the differential diagnosis includes the 'small round cell' tumor group, particularly metastatic small cell carcinoma and blastic hematological malignancies involving skin/soft tissues. Terminal deoxynucleotidyl transferase (TdT) is a DNA polymerase, which is a sensitive and specific antibody for ... http://merkel-cell-carcinoma.com/2008/05/28/tdt-expression-in-merkel-cell-carcinoma-potential-diagnostic-pitfall-with-blastic-hematological-malignancies-and-expanded-immunohistochemical-analysis/ Abstract: Pollheimer VS, Bodo K, Pollheimer MJ, Zigeuner R, Langner C. Merkel cell carcinoma metastasizing to the kidney mimicking primary neuroendocrine renal cancer. Case report. APMIS 2207;115:774-7. A 56-year-old male with a history of cutaneous neuroendocrine (Merkel cell) carcinoma presented with a solid mass of the left kidney, measuring 10 cm ... http://merkel-cell-carcinoma.com/2008/05/28/merkel-cell-carcinoma-metastasizing-to-the-kidney-mimicking-primary-neuroendocrine-renal-cancer-case-report/ Proceedings of the 1st Symposium of the Japanese Society for Ultrastructural Cutaneous Biology, Tokyo, 24-25 November 1999 Edited by H. Suzuki, Department of Dermatology, Surugadai Nihon University Hospital, 1-8-13 Kanda- urugadai, Chioyoda-ku, Tokyo 101-8309, Japan T. Ono, Department of Dermatology, Kumamoto University School of Medicine, 1-1-1 Honjyo, Kumamoto 860-8556, Japan Included in ... http://merkel-cell-carcinoma.com/2008/05/28/merkel-cells-merkel-cell-carcinoma-and-neurobiology-of-the-skin/ In the general population Merkel's cell carcinoma (MCC) is an aggressive neuroendocrine skin cancer. More than 600 cases have been reported. MCC seems to be common in transplant recipients, with 41 cases being reported to the Cincinnati Transplant Tumor Registry, and another 11 in the transplant literature. In the general ... http://merkel-cell-carcinoma.com/2008/05/28/merkels-cell-carcinoma-in-organ-recipients-report-of-41-cases/ Seventy patients with Merkel cell carcinoma were treated at Memorial Sloan-kettering Cancer Center between 1969 and 1989. The overall estimated 5-year survival rate was 64%. Factors predictive of improved survival included head and neck site and negative lymph nodes at presentation. Local recurrence was seen in 18 patients (26%) ... http://merkel-cell-carcinoma.com/2008/05/28/merkel-cell-carcinoma-prognosis-and-management/ Merkel cell carcinoma is a rare, malignant tumor of the skin characterized by significant incidence of local recurrence (30% to 45%), early involvement of the locoregional lymph nodes (40% to 70%) and distant metastases (30% to 50%) (17). Due to its aggressiveness and benign clinical appearance, the prognosis of this ... http://merkel-cell-carcinoma.com/2008/05/28/merkel-cell-carcinoma-6/ Merkel cell carcinoma is a skin cancer with 30% mortality and an incidence that has tripled in the past 15 years. There is agreement that surgical excision with negative margins is an appropriate therapeutic first step and that sentinel lymph node biopsy is a powerful prognostic indicator. Following excision of ... http://merkel-cell-carcinoma.com/2008/05/28/merkel-cell-carcinoma-5/